Handbook of Statistical Genetics (2 volume set)

The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genomewide Association Studies, Familybased Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance.As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive crossreferencing between the chapters, tying the different areas together. With heavy use of uptodate examples, reallife case studies and references to webbased resources, this continues to be musthave reference in a vital area of research.Edited by the leading international authorities in the field.David Balding Department of Epidemiology & Public Health, Imperial CollegeAn advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written WeightofEvidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, hes also had dozens of articles published in numerous international journals.Martin Bishop Head of the Bioinformatics Division at the HGMP Resource CentreAs well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics.Chris Cannings Division of Genomic Medicine, University of SheffieldWith over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Coeditor of the two previous editions of HSG, he also authored a book on this topic.